Programme

Programme overview [12/09/2022]

• Wednesday
  14 September WED
  14 Sep
• Thursday
  15 September THU
  15 Sep
• Friday
  16 September FRI
  16 Sep
• List of
  Posters List of
  Posters

• 12:00-19:00	Registration
  15:00-17:30	Council of Physiology Professors [Europa room]
  17:30-18:00	Opening Ceremony [Europa room]
  18:00-19:00	Opening Lecture [Europa room] Dennis Brown (Boston, MA, USA) A tale of fire and ice: the cell physiology of acid/base and water homeostasis by the kidney collecting duct epithelium
  19:00	Welcome cocktail

• 8:30-9:50	Parallel Symposia Symposium • Neurodegeneration and neuroprotection: gaining insights on underpinned molecular mechanisms using the retina as a benchmark [Europa room] Chair: Rosario Amato (Pisa) Rosario Amato (Pisa, Italy) Retinal ganglion cell dysfunction as an early marker in diabetic retinopathy James Tribble (Stockholm, Sweden) Nicotinamide improves metabolic resilience to provide neuroprotection in glaucoma Ilaria Piano (Pisa, Italy) Counteract oxidative stress and inflammation to delay the progression of Retinitis Pigmentosa Valeria Marigo (Modena-Reggio Emilia, Italy) Neuroprotection approaches targeting cell death mechanisms in Retinitis Pigmentosa
  	Symposium • Ca2+ signalling: unexpected new roles for the usual suspect [Scuderia room] Chairs: Andrea Gerbino (Bari), Francesco Moccia (Pavia) Francesco Lodola (Milan, Italy) Amphiphilic azobenzenes mediate optical modulation of excitation-contraction coupling in human induced pluripotent stem cell-derived cardiomyocytes Dmitry Lim (Novara, Italy) Calcium handling at the mitochondria-ER contact sites: role in Alzheimer's disease-related astroglial dysfunction and beyond Alessandra Fiorio Pla (Turin, Italy) TRPM8-Rap1 interaction plays a key protective role in angiogenesis and cancer cell migration Andrea Gerbino (Bari, Italy) TRPM1-induced lysosomal Ca2+ signals activate AQP2 translocation and water flux in the renal collecting duct
  	Symposium • Novel insights on the role of dopamine in learning and memory: from physiology to age-related and neuropsychiatric disorder [Federico II room] Chair: Livia La Barbera (Rome) Adrien Stanley (New York, NY, USA) The role of the tail of the striatum in safety learning Xabier Bujanda Cundin (Pozzuoli, NA, Italy) Mechanistic insights into the action of D1 receptors on memory in physiological and pathological conditions Maria Rosaria Tropea (Catania, Italy) Physiological role of dopamine D3 receptors in hippocampal synaptic plasticity and memory in physiological conditions and age-related disorders Livia La Barbera (Rome, Italy) Role of autophagy in VTA dopaminergic neurons in the pathophysiology of Alzheimer’s disease
  9:50-11:00	Parallel Oral Communications Oral Communications: Neurobiology and Neurophysiology 1 [Europa room] Chair: Daniela Pietrobon (Padua) Barbara Barile (Bari, Italy) AQP4 and cell migration: evidence for a proactive role of water channels in biomechanics in a model of reactive mouse astrocytes Daniele Bottai (Milan, Italy) Methylthiotransferase level impairment in NSCs as main effect of movement reduction Luigi Catacuzzeno (Perugia, Italy) A multiscale model of permeation and selectivity of the KcsA channel Maria Grazia Mola (Bari, Italy) AQP4 supramolecular assembly affects neural stem cell behavior Maria Cristina D`Adamo (Casamassima, BA, Italy) On the role of inwardly-rectifying potassium channel Kir4.1 in brain functions Danila Di Domenico (Pavia, Italy) In vivo investigation of cerebello-prefrontal cortex connections in anesthetized mice Mattia Lorenzo DiFrancesco (Genoa, Italy) Light-driven pore-complexation and membrane optoporation by a highly polarizable poly-conjugated compound
  	Oral Communications: Cell Physiology 1 [Scuderia room] Chair: Michele Maffia (Lecce) Andrea Barbuti (Milan, Italy) Characterization of metabolic properties of iPS-cardiomyocytes with a gain of function mutation in PITX2 gene linked to atrial fibrillation Amilcare Barca (Lecce, Italy) Insights into the endolysosome-resident SLC15A4/PHT1 peptide/histidine transporter as inflammation marker in the colonic epithelium of IBD patients with ulcerative colitis Giovanna Bastari (Rome, Italy) High neuroglobin levels impact on human neuronal differentiation and neurite network complexity Pasquale Bianco (Sesto Fiorentino, Italy) The force and power of a minimum ensemble of the atrial and ventricular myosin isoforms measured on the synthetic nanomachine Mariangela Centrone (Bari, Italy) Hyperosmolarity-induced cell shrinkage in renal cells: what role for RhoB farnesylation? Giorgia Chinigò (Turin, Italy) Structure-function analysis of Squaraines phototherapeutic activity: in vitro characterization of ROS and intracellular Ca2+ signals interplay in phototoxicity Alessandro Cospito (Milan, Italy) Striatin knock out induces a gain of function of INa current in mESC-derived cardiomyocytes
  	Oral Communications: Metabolism, Nutrition and Systems Physiology 1 [Federico II room] Chair: Giuseppe Calamita (Bari) Matteo Cerri (Bologna, Italy) Hibernation in humans: from anecdotal reports to evidence based Fabiano Cimmino (Naples, Italy) Oleoylethanolamide counteracts obesity-related metabolic and inflammatory alterations by modulating hepatic mitochondrial function in diet-induced obese mice Gianmarco Del Vecchio (Lecce, Italy) Nutrient acquisition in a lepr -/- zebrafish (Danio rerio) line Patrizia Gena (Bari, Italy) Aquaporin-9 (AQP9) has pathophysiological relevance in the systemic disorders caused by lysosomal acid lipase deficiency (LAL-D) Maria Concetta Granieri (Rende, CS, Italy) INF200, a selective inhibitor of NLRP3 Inflammasome, mitigates obesity-dependent metabolic impairment and induces cardioprotection by improving the myocardial endogenous antioxidant capacity in a rat model Giuliana La Rosa (Naples, Italy) Antioxidant and anti-inflammatory role of chlorogenic acid in human oligodendrocytes Alessandro Leone (Milan, Italy) Mediterranean diet is associated with a better estimated renal function in overweight adults with impaired fasting glucose
  11:00-11:30	Break
  11:30-12:30	pH Lecture [Europa room] Alexej Verkhratsky (Manchester, UK) Neuroglia in health and disease: from Golgi and Lugaro to modern days
  12:30-15:00	Lunch and Poster Session
  15:00-16:20	Parallel Symposia Symposium • Translating physiological research into innovative enterprises: a long and winding road? [Europa room] Chairs: Maria Svelto (Bari), Fabio Benfenati (Genoa) Laura Cancedda (Genoa, Italy) NKCC1 inhibition: from basic research to an innovative startup Elisabetta Ciani (Bologna, Italy) CDKL5 protein replacement therapy: the joint contribution of researchers and patients' families Stefano Di Marco (Genoa, Italy) Neurodegeneration and phytotherapy: a promising combination Fabio Benfenati (Genoa, Italy) From photostimulation of neurons to retina prosthetics
  	Symposium • Perception, action and visuomotor integration as essential components for world interaction [Scuderia room] Chair: Annalisa Bosco (Bologna) Paola Binda (Pisa, Italy) Active vision shapes ocular dominance Pablo Sanz Diez (Tuebingen, Germany) Motor adaptations for object size perception and grasping Annalisa Bosco (Bologna, Italy) Perceptual and kinematic variables are action predictors Antonella Maselli (Rome, Italy) Visually guided redirection of reaching actions reveals an enhanced efficiency of online motor corrections towards the body midline
  	Symposium • Nutrients and non nutrients and their impact on organ metabolism - an old story with new endings [Federico II room] Chairs: Luisa Cigliano (Naples), Arianna Mazzoli (Naples) Daniele Del Rio (Parma, Italy) Human metabolism of polyphenols and polyphenol effects on human metabolism: the story so far Arianna Mazzoli (Naples, Italy) Fructose induced metabolic alteration rescued by the “healthy diet”... or not? Marie Christine Simon (Bonn, Germany) Approaching personalized nutrition by tailoring the microbiome Luisa Cigliano (Naples, Italy) Impact of sugar intake on brain metabolism: does age matter?
  16:20-16:50	Break
  16:50-18:00	Parallel Oral Communications Oral Communications: Cell Physiology 2 [Europa room] Chair: Maria Carmela Cerra (Rende, CS) Anna De Bartolo (Rende, CS, Italy) The antioxidant Selenoprotein T relieves palmitate-induced cardio-lipotoxicity by reducing lipid accumulation, improving mitochondrial structure and respiration and reducing oxidative stress in H9c2 cardiomyocytes Annarita Di Mise (Bari, Italy) Generation of human collecting duct tubuloids of principal cells derived from ureteric bud organoids as differentiated cell models for physiology and disease modelling Mariacristina Filice (Rende, CS, Italy) Molecular signalling in the cardiac response to environmental hypoxia: lessons from the goldfish Carassius auratus Marco Fiocchetti (Rome, Italy) Neuroglobin in the extracellular milieu as mechanism of neuronal transmission of cell resilience Alessandra Galli (Milan, Italy) The nanotopography tunes the β-cell secretory activity by promoting cell connectivity and Ca2+ dynamics Fatima Maqoud (Bari, Italy) Beta 3 adrenergic receptor agonism increases AQP2 and NKCC2 trafficking/activation in human kidney tubules. A tool for bypassing genetic defects that prevent vasopressin-induced antidiuresis Antonio Michelucci (Perugia, Italy) Role of Ca2+-activated K+ channels in the regulation of cell volume in human glioblastoma cells
  	Oral Communications: Neurobiology and Neurophysiology 2 [Scuderia room] Chair: Patrizia Fattori (Bologna) Giuseppina D'Alessandro (Rome, Italy) Short-chain fatty acids promote the effect of environmental signals on the gut microbiome and metabolome in mice Miriana Scordino (Palermo, Italy) Manipulation of HSP70 expression modulates SH-SY5Y cell differentiation and susceptibility to oxidative stress-dependent cell damage Veronica Giusti (Padua, Italy) Atypical chemokine receptor 3: a novel player in astrocytes-mediated phagocytosis of synaptic terminals Francesca Grassi (Rome, Italy) Does dystrophin play a role in the development of the neuromuscular junction? Konstantinos Hadjidimitrakis (Bologna, Italy) Anterior-posterior gradient in the joint processing of arm movement direction and depth in primate parietal cortex Davide Martelli (Bologna, Italy) Two different inflammatory reflexes José Maya-Vetencourt (Pisa, Italy) The transcriptional repressor REST regulates plasticity of visual cortex circuitries
  	Oral Communications: Physiology of Motor Systems and Exercise [Federico II room] Chair: Roberto Bottinelli (Pavia) Gianluca Martinez (Sassari, Italy) A pilot gender-based study on the effects of in-ear music listening on treadmill and overground running biomechanics Vincenzo Lombardi (Sesto Fiorentino, Italy) Myosin filament activation in cardiac muscle and its regulation by physiological and pharmacological inotropic interventions Andrea Manca (Sassari, Italy) A novel measure of biological ageing based on multiple fitness tests is associated with risk scores for age-related diseases Silvia Zecchini (Milan, Italy) Rack1-dependent regulation of satellite stem cell homeostasis and skeletal muscle regeneration Letizia Zullo (Genoa, Italy) Motor adaptations in the octopus arm muscles: from motor units organization to myosin isoforms Francesca Ginatempo (Sassari, Italy) Inhibitory and excitatory intracortical circuits function differently in face and hand primary motor cortex Caterina Squarci (Florence, Italy) Passive and active mechanical properties of titin studied in intact frog muscle fibres upon inhibition of myosin motors by para-nitro-blebbistatin
  18:00-19:00	Herlitzka Lecture [Europa room] Marina Picciotto (New Haven, CT, USA) A novel VTA GABA pathway that encodes unconditioned reward value
  20:30	Musical Concert (Teatro Piccinni)
  	or (of your choice)
  19:45	A walk in “Bari Vecchia”

• 8:30-9:50	Parallel Symposia Symposium • Deciphering blood-brain barrier physiology: new mechanisms and translational opportunities [Europa room] Chair: Luca Maragliano (Ancona) Chiara Zurzolo (Paris, France) Reshaping connectivity with tunneling nanotubes Francesco Pisani (Bari, Italy) Tunneling nanotube-based super-cellularity between human blood-brain barrier cells: a new way to overcome the BBB? Luca Maragliano (Ancona, Italy) Computational modeling of Claudin complexes at the tight-junctions of biological barriers Valentina Castagnola (Genoa, Italy) Nanomaterials interactions with the blood-brain barrier
  	Symposium • A journey into the cardiac function and disfunction: from the extracellular milieu to the nuclear envelope [Scuderia room] Chairs: Monica Carmosino (Potenza), Tommaso Angelone (Cosenza) Pasquale Pagliaro (Turin, Italy) Role of NLRP3 inflammasome in cardioprotection Leonardo Sacconi (Florence, Italy) Cardiac t-tubules: a membrane domain with peculiar electrical properties and excitability Antonio Zaza (Milan, Italy) SERCA function and Ca2+ store stability Monica Carmosino (Potenza, Italy) Role of nuclear Lamin A/C in cardiomyocyte homeostasis
  	Symposium • Advances on neurotransmitter systems involved in mechanisms of neural modulation: tracing common threads in homeostatic responses, synaptic plasticity and diseases [Federico II room] Chairs: Giuditta Gambino (Palermo), Valentina Di Liberto (Palermo) Valentina Di Liberto (Palermo, Italy) Activation of muscarinic acetylcholine receptors modulates neuronal plasticity and survival: implications for therapeutic interventions in neuropsychiatric and neurodegenerative disorders Giuditta Gambino (Palermo, Italy) Nitrergic modulation of cannabinoid-TRPV1 signalling in the hippocampus: impact on neuronal hyperexcitability and synaptic efficiency Gabriele Ruffolo (Rome, Italy) Neuroinflammation and GABAergic function: a complex relationship Giada Mascio (Pozzilli, Italy) Perineuronal nets are under the control of type-5 metabotropic glutamate receptors in the developing somatosensory cortex
  9:50-11:00	Parallel Oral Communications Oral Communications: Neurobiology and Neurophysiology 3 [Europa room] Chair: Iole Tommassini Barbarossa (Cagliari) Melania Melis (Monserrato, CA, Italy) Machine learning applications in physiology and diseases of taste Laura Civiero (Padua, Italy) Trafficking of the glutamate transporter is impaired in LRRK2-related Parkinson's disease Alessandra Ottaviani (Pavia, Italy) High-density multielectrode array recordings reveal computational complexity in cerebellar cortical processing Fabiola Paciello (Rome, Italy) Auditory sensory deprivation affects memory causing hippocampal dysfunctions in a mouse model of Alzheimer’s Disease Eleonora Pali (Pavia, Italy) Dendritic processing implements spike-timing dependent plasticity (STDP) in cerebellar Golgi cells Roberto Piacentini (Rome, Italy) Altered gliotransmitter handling by astrocytes mediates tau-induced synaptic dysfunction in hippocampal neurons Giulio Sancini (Monza, Italy) Multifunctional liposomes acting at the Neurovascular Unit rescuing the impaired functions in AD
  	Oral Communications: Metabolism, Nutrition and Systems Physiology 2 [Scuderia room] Chair: Antonia Lanni (Caserta) Assunta Lombardi (Naples, Italy) Role of ketone bodies in energy metabolism: focus on brown adipose tissue Ciro Menale (Naples, Italy) Mitochondria dynamics and function dictate osteoblast metabolism in response to nutrients Vincenzo Migliaccio (Fisciano, SA, Italy) Physiological adaptations and tissue damage induced by a simultaneous chronic exposure to environmental pollutants and hyperlipidic diets: focus on mitochondrial and cellular stress in rat model Serena Milano (Bari, Italy) β3-adrenoreceptor as a new player in renal regulation of acid-base homeostasis Giuseppe Petito (Caserta, Italy) Mechanism linking miR-18a-5p/SREBP1/PERK axis and endoplasmic reticulum stress to liver dysfunction in rats fed on high-fat diet Francesca Piccapane (Bari, Italy) Development of a 3D model of mucus-secreting colon epithelium to study the interaction with human gut microbiota in physio-pathologic conditions Eriola Hoxha (Turin, Italy) Role of membrane lipid composition in synaptic transmission
  	Oral Communications: Cell Physiology 3 [Federico II room] Chair: Mirko Baruscotti (Milan) David Molla (Milan, Italy) Analysis of the dominant negative effect observed in a compound heterozygosity mutation (K1578N-G1866fs) of the Nav1.5 cardiac sodium channel Serena Nencini (Siena, Italy) Effects of placental secretome on astrocytes' activity Paola Maura Tricarico (Trieste, Italy) AQP3 expression and localization is altered in the epidermis and hair follicles of Hidradenitis suppurativa patients Sofia Passaponti (Siena, Italy) The role of the placenta on the RANK/RANKL/OPG axis Marianna Ranieri (Bari, Italy) Receptor-receptor interactions of the G protein-coupled receptors V2R and CaSR as potential regulators of multiple signaling pathways in renal cells Luca Palloni (Milan, Italy) The role of AMPK in HCN4 membrane expression Simona Scorza (Bari, Italy) Kidney in a box: using a millifluidic perfusion bioreactor to develop a 5D in vitro model for studying the beta-adrenergic system in the collecting duct epithelium Claudia Tonini (Rome, Italy) Epigenetic modulation of lipid homeostasis: the case of BET proteins
  11:00-11:30	Break
  11:30-12:30	Plenary Lecture [Europa room] Nicola Brunetti-Pierri (Naples, Italy) Development of novel therapies for inborn errors of metabolism: from understanding metabolic pathways to proof-of-concept studies
  12:30-15:00	Lunch and Poster Session
  15:00-16:00	Ruzzier Lecture [Europa room] Giorgio Carmignoto (Padua, Italy) Astrocytes at the center of the brain of neurons
  16:00-16:30	Break
  16:30-19:00	SIF Assembly [Europa room]
  20:30	Social dinner (Masseria Pietrasole)

• The two poster sessions are scheduled for Thursday, 15 September, and Friday, 16 September, from 12:30 to 15:00. In each day, the presenting authors of odd-numbered posters must be present from 13:30 to 14:15 and those of even-numbered posters from 14:15 to 15:00.

  When preparing your poster please remember that the poster's maximum size is 80 x 110 cm, width x height.

  Correct format...      Wrong format...

  Posters must be mounted on the day of the presentation only and removed before 18:30 on Thursday and within 16:30 on Friday. Posters from the Thursday session that are still up by Friday at 08:00 will be discarded by the venue personnel so that the Friday posters can be set up.

  •    D A Y   1   
  •    D A Y   2   

  • Poster Session 1 • 15 September • 12:30-15:00

    Cell Physiology

    P1.1 Cristiana Alberghina (Catania)
    Heterocellular communication mediated by irradiated microglia sustains glioblastoma growth and proliferation
    
    P1.2 Marco Alves (Oporto, Portugal)
    Glucose stimulates in vitro production of insulin by human spermatozoa
    
    P1.3 Martina Arici (Milan)
    Istaroxime follow-on compounds: a new class of selective SERCA2a activators as first-in-class drug candidates for heart failure treatment
    
    P1.4 Raquel Bernardino (Oporto, Portugal)
    Hyperestrogenism modulates aquaglyceroporins function in mouse Sertoli cells: implications for male fertility
    
    P1.5 Gregorio Bonsignore (Alessandria)
    Could the intracellular redox state become the Achilles heel for the malignant mesothelioma?
    
    P1.6 Giuseppe Calamita (Bari)
    Gene deletion of Aquaporin-9 normalizes oxidative stress and improves survival in a bacterial endotoxin induced mouse model of sepsis
    
    P1.7 Maria Cerra (Arcavacata di Rende, CS)
    The ACE2-Alamandine axis modulates the cardiac performance of the goldfish Carassius auratus
    
    P1.8 Filippo Conca (Pavia)
    Studying nuclear signalling events in skeletal muscle fibers
    
    P1.9 Patrizio Cracco (Rome)
    Triggering neuroprotective pathways to prevent neurodegeneration: role of resveratrol/estrogen receptor β/neuroglobin signaling
    
    P1.10 Mariagrazia D'Agostino (Bari)
    Short-term actions of dDAVP on the AQP3 expression and function in human colon HCT8 cells
    
    P1.11 Simona D'Aprile (Catania)
    Iron overload reduces cell survival, metabolic activity and modulates CD71 levels in thyroid cancer cells
    
    P1.12 Daria Di Molfetta (Foggia)
    A 3D organotypic model of human pancreatic ductal epithelium for investigating the role of Na⁺/H⁺ Exchanger 1 and pHe in the pancreatic branching morphogenesis
    
    P1.13 Angela Ferrulli (Bari)
    Calcium Sensing Receptor and Polycystin-2 direct interaction: implication in Autosomal Dominant Polycystic Kidney Disease (ADPKD)
    
    P1.14 Sabino Garra (Bari)
    White blood cells aquaporins AQP3 and AQP9 are implicated in NLRP3 inflammasome dysfunction underlying Familial Mediterranean Fever (FMF)
    
    P1.15 Maria Elena Giordano (Lecce)
    Apoptotic Volume Decrease (AVD) in A₅₄₉ cells exposed to a water-soluble fraction of Particulate Matter (PM₁₀) 
    
    P1.16 Simone Guarnieri (Chieti)
    GAP43 is a key player in intracellular Ca²⁺dynamics and oxidative balance in cardiomyocytes
    
    P1.17 Federica Impellitteri (Messina)
    Physiological and histopathological alterations in Mytilus galloprovincialis exposed to tebuconazole
    
    P1.18 Lillà Lionetti (Fisciano, SA)
    Antioxidant effect of hydroxytyrosol, a phenolic compound from virgin olive oil, against cellular damage induced by the environmental pollutant dichlorodiphenyldichloroethylene (DDE) in HepG2 cells
    
    P1.19 Maria Giulia Lionetto (Lecce)
    Motility of Mytilus galloprovincialis hemocytes: perspectives for its use as cellular function sensitive to the exposure to pharmaceuticals in the environment in non-target organisms
    
    P1.20 Debora Lo Furno (Catania)
    Functional applications of Pericyte-like differentiated human adipose-derived mesenchymal stem cells
    
    P1.21 Simona Lobasso (Bari)
    Beneficial effects of mitochondria-targeted small peptide SS-31 for improving cardiac mitochondrial function in tafazzin knockdown mice
    
    

    Metabolism, Nutrition and Systems Physiology

    P2.1 Pasquale Calvi (Palermo)
    The positive impact of Aphanizomenon flos aquae supplementation on insulin-resistance and hepatic steatosis in the HFD-obese mice
    
    P2.2 Monica Canepari (Pavia)
    Molecular determinants of diaphragm muscle impairment in a mouse model of Spinal Muscolar Atrophy 
    
    P2.3 Lucantonio Debellis (Bari)
    Soy metabolism by gut microbiota from patients with precancerous intestinal lesions
    
    P2.4 Nevia Dule (Milan)
    Pancreatic PCSK9 controls glucose homeostasis by modulating the β-cell secretory apparatus via LDLR-cholesterol axis
    
    P2.5 Leonardo Ermini (Siena)
    Bisphenol A triggers the placental release of nanovesicles containing signals that support the homeostasis of fetal heart cells
    
    P2.6 Gianluca Fasciolo (Naples)
    Hyperthyroidism and insulin resistance in rat liver: the role of ROS
    
    P2.7 Andrea Foppiani (Milan)
    Puberty seems associated with increased insulin secretion in cystic fibrosis patients
    
    P2.8 Elena Grossini (Novara)
    Role of the oxidative stress in in pregnancy arising in old age. Focus on human mesenchymal stem cells from umbilical cords (huMSCs)
    
    P2.9 Sara Mambrini (Milan)
    Effects of acute administration of an extract of Phaseolus Vulgaris on the glycometabolic pattern in subjects with obesity
    
    

    Neurobiology and Neurophysiology

    P3.1 Natalia Abate (Naples)
    Secretion of Cystatin B by synaptosomes isolated from rat brain and human cerebral organoids
    
    P3.2 Pasqua Abbrescia (Bari)
    Evaluation of the role of AQP4 isoforms in cerebral water homeostasis
    
    P3.3 Anna Maria Aloisi (Siena)
    Bisphenol A exposure during pregnancy affects ER and AR brain receptors differently in male and female fetuses
    
    P3.4 Roberto Barbaro (Bari)
    Toward an in vitro model for studying molecular mechanism underlying motor neuron diseases
    
    P3.5 Gerardo Biella (Pavia)
    Effects of oxytocin on action potential and neural coding of neurons in hippocampal CA1 and dorsal striatum in mice
    
    P3.6 Elisabetta Catalani (Viterbo)
    Analysis of retinal ganglion cell impairments and rescue in hyperglycaemic mice treated with the somatostatin analogue octreotide
    
    P3.7 Francesca Corsi (Pisa)
    Retina as a tool in the assessment of the efficacy of saffron Repron treatment in a model of neurodegeneration Alzheimer's like
    
    P3.8 Giulia Curia (Modena)
    In vivo evaluation of the anti-inflammatory activity of alginate during brain repair in the temporal lobe epileptic rat
    
    P3.9 Francesca De Chirico (Bologna)
    Understanding the role of microglial extracellular vesicles in neuroinflammation spreading: an in vitro study
    
    P3.10 Fabio Di Bello (Rome)
    Dynamic interplay between covertly attended events and saccade targets in macaque prefrontal cortex
    
    P3.11 Marco Emili (Bologna)
    Adolescent treatment with a β2-adrenergic receptor agonist improves hippocampal dendritic maturation and behaviour in the Ts65Dn mouse model of Down syndrome
    
    P3.12 Daniele Gallo (Palermo)
    Guanosine modulates K⁺ membrane currents in SH-SY5Y cells: involvement of Adenosine signalling
    
    P3.13 Alfonso Gravante (Parma)
    Role of monkey prefrontal, premotor cortices and basal ganglia in guiding behavior based on social information
    
    P3.14 Donatella Lobraico (Bari)
    Aquaporin-4 water channel as a novel modulator of odorant-evoked response in the olfactory system
    
    P3.15 Nicola Loi (Sassari)
    Role of interhemispheric interactions at the level of the hand primary motor cortex in the processing of emotional face expressions
    
    P3.16 Serena Losacco (Genoa)
    The puzzle of fibromyalgia explained by a pathophysiological bistable switch model
    
    P3.17 Alessia Manca (Sassari)
    Testing the effectiveness of a new acetylcholinesterase inhibitor for alzheimer’s disease in drosophila melanogaster transgenic model 
    
    P3.18 Francesca Massenzio (Bologna)
    Neuroinflammation in Fabry’s disease: a new insight into a multisystemic disease
    
    

    Physiology of Motor Systems and Exercise

    P4.1 Veronica Farinelli (Milan)
    Postural assessment in hereditary spastic paraparesis
    
    P4.2 Edoardo Lecce (Rome)
    The acute effects of whole-body vibration on motor unit recruitment and discharge properties
    
    P4.3 Silvia Marchese (Milan)
    Pediatric slow-progressive cerebellar atrophy (but not non-progressive hypoplasia) delays intra-limb anticipatory postural adjustments
    
    P4.4 Mauro Raia (Palermo)
    Modulation of human motor cortical excitability and plasticity by Opuntia Ficus Indica fruit consuption: evidences from non-invasive brain stimulation and rs-fMRI
    
    

  • Poster Session 2 • 16 September • 12:30-15:00

    Cell Physiology

    P1.22 Michele Maffia (Lecce)
    The tug of war governing proteostasis in α-synucleinopathies 
    
    P1.23 Rosanna Mallamaci (Bari)
    Olive tree bioactives: phenolic compounds with hormone-like activities
    
    P1.24 Giuliana Mannino (Messina)
    Anti-oxidant effects of Açaì extract (Euterpe oleracea) on human adipose-derived mesenchymal stem cells
    
    P1.25 Angela Marino (Messina)
    Morphological and functional alterations in H₂O₂-treated erythrocytes: role of quercetin
    
    P1.26 Simona Martinotti (Alessandria)
    GRP78: the needle of the scale of a delicate equilibrium between survival and cell death
    
    P1.27 Aurora Mazzei (Lecce)
    Assessment of a Caco-2/THP-1 derived macrophages co-culture model for investigating SLC15A4/PHT1 gene expression in the cross-talk between intestinal epithelial monolayer and immune cells in a common inflammatory framework
    
    P1.28 Emiliano Montalesi (Rome)
    Biomedical implications of Estrogen/Neuroglobin pathway modulation exerted by Resveratrol Conjugated Gold Nanospheres
    
    P1.29 Rossana Morabito (Messina)
    Targets of oxidative stress in the aging neuroglia: functional role of Kir2.1 channel
    
    P1.30 Anas Munir (Lecce)
    Treating neurodegenerative proteinopathies with a vintage therapy: Insulin as a potential neuroprotective agent
    
    P1.31 Giusy Pietrafesa (Potenza)
    Rescue of the cell function in cardiomyocytes expressing the R321X LMNA variant by nonsense mutation readthrough and the ER stress inhibition
    
    P1.32 Gregorio Polo (Lecce)
    In vitro sensitivity of carbonic anhydrase activity to paracetamol in the model organism Daphnia magna
    
    P1.33 Elia Ranzato (Alessandria)
    Endothelial integrity restoration: the response boosted by platelet lysate involving calcium toolkit
    
    P1.34 Giorgia Rastelli (Chieti)
    Store Operated Calcium Entry (SOCE) is enhanced in skeletal muscle during development
    
    P1.35 Alessia Remigante (Messina)
    Oxidation stress as a mechanism of aging in human erythrocytes: protective effect of Açaì (Euterpe oleracea) extract
    
    P1.36 João Ribeiro (Oporto, Portugal)
    CFTR as a modulator of AQP7-mediated membrane permeability in human sperm
    
    P1.37 Carmine Rocca (Arcavacata di Rende, CS)
    Impact of the possible cross-talk between endogenous selenoprotein T and its mimetic antioxidant peptide, PSELT, in precondition the heart against tunicamycin-mediated Endoplasmic-Reticulum stress during ischemia/reperfusion damage
    
    P1.38 Laura Simone (San Giovanni Rotondo, FG)
    AQP4-containing extracellular vesicles affect the phenotype of surrounding cells
    
    P1.39 Sara Spinelli (Messina)
    Age-related oxidative stress impairs the activity of Kv3.1 channel
    
    P1.40 Federica Spitale (Catania)
    6-azido-6-deoxy-D-glucose conjugated nanoparticles as a tool to target central nervous system
    
    P1.41 Sakthi priyan Venkatesan (Novara)
    Membrane blue dual protects retinal pigment cells and ganglionic cells against ultraviolet-induced damages through modulation of mitochondrial function
    
    P1.42 Agata Zappalà (Catania)
    Pannexin 3 expression in human adipose-derived mesenchymal stem cells during osteogenic differentiation
    
    

    Metabolism, Nutrition and Systems Physiology

    P2.10 Caterina Miro (Naples)
    Thyroid hormone regulates glutamine metabolism and anaplerotic fluxes by inducing mitochondrial glutamate aminotransferase GPT2
    
    P2.11 Gaetana Napolitano (Naples)
    Red synthetic and natural food dyes affect the redox state of Artemia salina nauplii
    
    P2.12 Lucrezia Polimeno (Bari)
    Anisakis allergy: is aquacultured fish a safe and alternative food to wild-capture fisheries for Anisakis simplex-sensitized patients?
    
    P2.13 Rita Polito (Foggia)
    Effects of Very Low-Calorie Ketogenic Diet on sympathetic nervous system through Heart Rate Variability (HRV) evaluation
    
    P2.14 Giorgia Sollai (Monserrato)
    Relationships among olfactory function, lifestyle and BMI in elderly subjects
    
    P2.15 Giovanna Trinchese (Naples)
    Dietary milk supplement affects hepatic lipid and glucose metabolism, inflammatory and redox state engaging two hepatocyte aquaporins, AQP8 and AQP9
    
    P2.16 Giovanna Valenti (Bari)
    Alteration of vasopressin-aquaporin system in hindlimb unloaded mice
    
    P2.17 Maria Chiara Valerii (Bologna)
    Nutritional modulation of human colonic physiology by using essential oils
    
    

    Neurobiology and Neurophysiology

    P3.19 Alberto Melecchi (Pisa)
    Neurodegeneration and vascular dysfunction: clues from a mouse model of glaucoma
    
    P3.20 Daniela Meleleo (Bari)
    Role of calcium ions in the aggregation process of hIAPP. Possible implications in T2DM
    
    P3.21 Valentina Melfi (Milan)
    Locomotor Activity, Nerve Conduction and Mitochondrial Activity in Skeletal Muscle are affected by Atorvastatin: Evidence from ApoE-/- Mice
    
    P3.22 Tasnim Mohamed (Milan)
    DNA methyltransferases and histone deacetylases: the epigenome controls SCs differentiation
    
    P3.23 Claudio Molinari (Vercelli)
    Brain aging mechanisms and BDNF, brain derived neurotrophic factor
    
    P3.24 Alessandra Occhinegro (Bologna)
    Sleep deprivation during the recovery from synthetic torpor enhances Tau protein dephosphorylation in the rat brain
    
    P3.25 Claudia Palazzo (Bari)
    Isolation and proteomic characterization of exosomes as predictive biomarker in patients with Multiple Sclerosis
    
    P3.26 Eleonora Palma (Rome)
    GABA_A receptors function is modulated by IL-1β in epileptic human tissues
    
    P3.27 Roberta Pati (Bari)
    Phosphorylation as a short-term regulation mechanism of the readthrough isoform AQP4ex
    
    P3.28 Eleonora Poeta (Bologna)
    Impaired bioenergetic profile and proliferation in Neuron Progenitor Cells (NPCs) from iPSCs of patients affected by AGC1 deficiency
    
    P3.29 Umberto Quartetti (Palermo)
    Modulating boundary of peripersonal space by mean of virtual reality and augmented reality
    
    P3.30 Milena Raffi (Bologna)
    Motor control evaluation in diabetic subjects
    
    P3.31 Daniela Ratto (Pavia)
    Boosting recognition memory with Hericium erinaceus metabolites
    
    P3.32 Tiziana Romanazzi (Varese)
    Investigation of the interaction between bile acids and the dopamine transporter DAT
    
    P3.33 Carla Russo (Rimini)
    Administration of the BDNF mimetic 7,8-Dihydroxyflavone during adolescence rescues neuron maturation and improves hippocampus-dependent memory in the Ts65Dn mouse model of Down syndrome
    
    P3.34 Silvia Russo (Bari)
    Assessing age related changes in mouse olfactory system
    
    P3.35 Giulia Terribile (Monza)
    Diesel exhaust particles in the onset and progression of neuroinflammation
    
    P3.36 Giovanna Zoccoli (Bologna)
    Impact of perinatal exposure to Chlorpyrifos pesticide on breathing phenotype of adult mice
    
    

    Physiology of Motor Systems and Exercise

    P4.5 Maira Rossi (Pavia)
    Nitrate supplementation attenuates neuromuscular dysfunctions in age-related sarcopenic mice
    
    P4.6 Martina Scalia (Latina)
    Comparison of acute responses in spinal excitability between older and young people after neuromuscular electrical stimulation
    
    P4.7 Jorge Storniolo (Milan)
    Whole-body cryotherapy boosts exercise performance by shifting the sympathovagal balance toward vagal predominance
    
    P4.8 Anna Valenzano (Foggia)
    Physical activity modulates Orexin-A serum levels in diabetes mellitus subjects